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Description

Aryl hydrocarbon receptor-deficient mice develop heightened inflammatory responses to cigarette smoke and endotoxin associated with rapid loss of the nuclear factor-kappaB component RelB

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This contrasts with the heterogeneous toxicity of GPX4 inhibitors, which have previously shown resistance in certain NE subtypes 40

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The therapeutic efficacy of Ebselen has been studied in experimental diabetic models (de Haan and Cooper 2011)

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