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GHK-Cu has been shown to be more effective than most prescription retinols for reversing skin thinning, without the irritation, purging, or photosensitivity issues that come with retinol-based products

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To verify the involvement of 26 S proteasome machinery on unglycosylated proIGF-1Ea degradation, we subsequently treated IGF-1Ea-transfected HEK293 cells with proteasome inhibitor MG132

Both studies need further confirmation on larger cohorts