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Two older studies published in 1981 and 1986 described mixed results in the intestinal histologic response of 7 patients with celiac disease and dermatitis herpetiformis after a trial of elemental diet despite significant improvement in their skin lesions, although these studies were limited by having used Crosby-Kugler capsules to obtain the small bowel biopsies [28, 29]

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Tran et al., 2025), creating substantial risks to global food security as demand is projected to rise by 50% by 2050 (Tern et al., 2024)