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[4] It is suggested that upon binding to the GHRH receptor, Tesamorelin & Mod GRF may induce conformational changes in the receptor structure, potentially activating intracellular signaling pathways

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We also examined liver function of mice after specific knockout of HK2 in hepatocytes, H&E and tunel staining of the liver showed that specific knockdown of HK2 in hepatocytes did not cause hepatocyte death and liver damage (Supplementary Fig