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Experts say the unauthorized products fall into regulatory grey zone, with limited evidence of safety and risks that include hormonal imbalances, the growth of cancerous tumours, and liver or kidney damage

In research contexts, the complex has been explored for its potential to support extracellular matrix maintenance, barrier quality, and tissue remodeling signals, particularly when formulated for topical presentation

Another study providing pharmacological evidence of altered MTs regulation and its impact on Zn homeostasis in obesity was conducted by Mota Martins et al

These results suggest that reduced homocysteine causes protein thiol homocysteinylation that may induce smooth muscle cell proliferation by binding to a redox receptor and that may exacerbate atherosclerotic lesion formation by inducing collagen expression (Tyagi, 1998)