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The catalases contain four heme subunits with Fe 2+ ions undergoing oxidation and catalyze the dissociation of two H 2 O 2 molecules into water and oxygen (Arora et al., 2002)

21 Possible role of the GPX4 gene in the development of CS A possible role of glutathione peroxidase-4 in the development of CS has been summarized in Figure 1

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When evaluating the stability in the presence of HSA at 35 mg/mL (reflecting the average plasma concentration of HAS), results showed that the FA-CMC-GNA NPs size remained stable over the 72-h period, with an average diameter maintained at 305.4 nm and no observable aggregation