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It should be noted, that almost all the patients recruited were at an early stage of diabetic retinopathy with DME and had good visual acuity at baseline so a larger average increase in acuity would not be expected

Protein Pept Lett 24:190196 Tan J, Huang J, Huang Y, Chen Y (2014) Effects of single amino acid substitution on the biophysical properties and biological activities of an amphipathic -helical antibacterial peptide against Gram-negative bacteria