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PMCID: PMC8398778

Subsequently, pharmacologic inhibition of CD38 in LPS and IFN stimulated primary human astrocytes, phenocopied the murine studies and showed that the inhibition of NAD + hydrolysis in these cells, decreased chemokine signaling (72), supporting that astrocytic NAD + biology may play an important role in human neuroinflammation

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In esophageal squamous cell carcinoma, arsenic-iron oxide conjugate nanocomposites effectively degrade YAP, significantly sensitizing tumor cells to radiotherapy and chemotherapy (117)