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ChlaDUB1 was reported to suppress NF-B signaling by binding to the inhibitor IB-, preventing its ubiquitination and subsequent proteasomal degradation 46

When the majority of that literature originates from a single research group, uses the same animal model, and has not been independently replicated, the effective evidence base is narrower than the publication count implies

293 Supplementation of the diet of high-risk surgical patients with an immune-enhancing diet (IED) containing arginine reduces the incidence of infection and increases macrophage phagocytosis, IL-2 expression, and CD4 + T cell numbers