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408: Repeated Dose 90-Day Oral Toxicity Study in Rodents

In the same line, retinal degeneration is a clinical entity associated with several ciliopathies 178 and mutations in POC1B , encoding a protein involved in the function of photoreceptor primary cilia, are well known to be associated with JBTS 178 and conerod dystrophy (CORD)

Sulfonamide non-antimicrobials do not have a N1 heterocyclic ring as this group is responsible for antimicrobial activity and most do not contain the N4 aryl-amine