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Lancet 1963;1:785-9.ArticlePubMed 53

Abstract In every cell, several redox reactions occur, leading to free radical formation like reactive oxygen species (ROS), reactive nitrogen species (RNS), and reactive sulphur species (RSS)

More recently, by using conditional disruption of the gene in mouse livers, my group has been able to provide a more detailed examination of the roles of TrxR1 for replication in animal cells (Rollins et al., 2010