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Peucedanum ostruthium shows anti-tubercular potential in silico, with nine bioactive compounds mapped to 256 TB-related genes

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Cytotoxicity assays, including MTT and SRB, showed significantly reduced toxicity for the PEGylated nanoparticle formulation compared to free tolcapone (cell viability exceeded 85% at 10, 25, and 50 M of the formula after 24 and 48 h of treatment)