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The goals of treatment are to reduce inflammation, eradicate infection, improve drainage and aeration of nasal and sinus mucosa, and restore mucociliary function.2 Common medical therapies for acute rhinosinusitis include antibiotics, nasal saline irrigation, decongestants, antihistamines, mucolytics, topical or systemic corticosteroids, and anti-inflammatory drugs

Melatonin has emerged as an important adjunct in combating OA due to its suppressing oxidative stress caused by iron overload (Yang et al., 2017)

se responsabilizan, en parte, el estreptococo grupo B (GBS) y Escherichia coli entre las principales causas

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