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Proc Natl Acad Sci USA 74:34243428 Gibson CL, Clowry GJ (1999) Transient expression of calcitonin gene-related peptide immunoreactivity in the ventral horn of the post-natal rat cervical spinal cord

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The study found no significant differences in systemic side effects between routes, but noted that injection site reactions were the leading cause of treatment discontinuation (3% of injectable users versus 1% of oral users discontinuing due to GI upset)