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Data availability The data that supports the generation of oligonucleotides used in this study are openly available in Zenodo.org at The molecular evolutionary relations, ligand tracing and tracking of defined sequences through successive selection rounds were performed using COMPAS software (AptalT GbmH, Planneg, Germany) 41,42

Safety Adverse effects In the United States, turmeric is generally recognized as safe (GRAS) by the FDA as a food additive (110)

Diverging from its original intent offers an opportunity to repurpose previously approved drugs to treat other ailments

"A prion accelerates proliferation at the expense of lifespan"