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Melanotan-1's linear structure and D-Phe7 substitution optimize MC1R interactions, explaining its focused pigmentation and photoprotective effects

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In many junctional or compound Spitz's nevi, fascicles of spindle cells are arranged in tight fascicles parallel to epidermal rete ridges in a pattern that has been likened to hanging bananas ( Fig

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Perifollicular hypopigmentation with resultant clinically scalloped borders or variegation in pigmentation also was a hallmark feature

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