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doi: 10.21037/tau-20-999 5 HaoYGeHSunMGaoY

PKLR promotes colorectal cancer liver colonization through induction of glutathione synthesis

In this study, the production of mtROS is derived from low-level, sustained ROS signaling generated by reverse electron transfer (RET) following partial inhibition of ATP synthase, whereas typical IBD pathology is characterized by high levels of ROS