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On the other hand, if the evidence of only minute stomach lesions with intraoral application at the tongue and swallowed, was not the immediate overlapping cytoprotection/adaptive cytoprotection continuously operating in the stomach, the stomach would have much more lesions from the double volume of the strong alcohol (alcohol at tongue, swallowed + alcohol intragastrically)

Olaussen RW, Lvik A, Tollefsen S, Andresen PA, Vatn MH, De Lange T et al

Accordingly, irAEs are expected to appear in patients treated with anti-CTLA-4 (6085%), anti-PD-1 (1637%), and anti-PD-L1 (1224%)

Doi A, Sakasaki J, Tokunaga C, et al