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Once activated, AMPK enhances the function of 2,3-bisphosphoglycerate mutase (2,3-BPGM), the enzyme responsible for producing 2,3-bisphosphoglycerate (2,3-BPG), a molecule that decreases hemoglobins oxygen affinity and promotes oxygen release to tissues

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These cases often occur in people without a family history of autoimmune gastritis

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