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doi: 10.1152/physrev.00040.2012 114 BaschieriAJinZAmoratiR

Because it is highly specific, it offers a refined tool for metabolic optimization

Elevated intra-articular iron levels and altered expression of ferroptosis-related molecules such as ACSL4 and GPX4 have been associated with the severity of joint pain, cartilage damage, and functional decline ( In summary, ferroptosis is a shared pathological mechanism across multiple joint tissues in OA