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Description

In organotypic midbrain-striatum co-cultures increase in midbrain SOD activity increases the resistance of dopaminergic neurons to NO cytotoxicity via suppressing the formation of peroxynitrite (Katsuki et al., 2001)(Tabrizi et al., 2020)

It helps eliminate toxins and harmful substances from the body, promoting the proper functioning of detoxification organs such as the liver and kidneys

2020;12:CD009861

mHTT impairs mitochondrial biogenesis, disrupts calcium handling, and promotes fission over fusion, leading to fragmented and inefficient mitochondria