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Stress Response & HPA Axis Regulation: Evaluating how the peptide modulates the endocrine response to physical and psychological stressors, particularly its influence on adrenocorticotropic hormone (ACTH) and cortisol secretion

Exercise represents a subset of physical activity that is planned, structured, and repetitive and has, as final or intermediate objective, the improvement or maintenance of physical fitness, physical performance, or health ( The molecular basis of responses to acute and chronic exercise training have been extensively studied both in humans and in mice affected by ALS

Acknowledgments We thank Dr Pingzhao Zhang for providing us critical advice

Taken together, these findings highlight a model in which NMS-induced oxidative and inflammatory stress disrupts hippocampal neurogenesis, and NAC restores the neurogenic capacity by rebalancing redox and glial homeostasis