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Citation46 The overproduction of ROS and oxidative damage to cellular macromolecules are considered as key mechanisms of the nanoparticles biotoxicity

CRM and other skin diseases CRM resolves changes at the cellular and subcellular level comparable to that obtained with standard histology

Solvent A was prepared by mixing 99 mL of Milli-Q (Millipore) water and 1 mL of 1 mol/L ammonium bicarbonate and was adjusted to a pH of 9.2 with 25% ammonium hydroxide (~0.1 mL)