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Nature Communications , 7 , 10305

To examine whether the decreased FASN levels could result from NOTCH inhibition, we assessed the level of Notch signaling by identifying the levels of NOTCH1, NOTCH2, and their most direct downstream effector, HES1 (43), in GSH-depleted livers

The enhancement in oxidative decarboxylation would increase cytochrome C level and therefore improve the mitochondrial membrane potential, function, and biogenesis