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If DNA synthesis and/or methylation (epigenetic events) are altered in utero, this could affect gene expression thus impacting fetal development and that could modulate the fetal susceptibility to various diseases

As background, the Food and Drug Act in sec 503A provides that bulk drug substances that either 1) lack a USP or NF monograph, or 2) are not components of FDA-approved drug products, cannot be used in compounding unless they appear on a list created under Section 503A

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The extent of deviation can also cause pain, especially during sex, as well as erectile dysfunction