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This involves clinical checks, lab tests, and risk assessments

Table 4 lists the correlations of urinary metal excretion with one another at baseline, Table 5 lists the correlations at 9 th dose of Phase 1, and Table 6 lists the correlations at 9 th dose vs

Bhatia M, Suliman H, Ahmed R, Kostadinov D, Singhal T

pH IOP leads to abnormal accumulation of ferrous iron and pro-ferroptotic factors including lipid peroxidation and ACLS4, and depletion of anti-ferroptotic factors, such as GSH, GPX4, and nicotinamide adenine dinucleotide phosphate, in RGC cells and retinas via NCOA4/FTH1 axis, thus disrupting iron metabolism and leading to ferroptosis in RGCs during glaucoma (Yao et al., 2023)