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Twelve highly efficacious drugs with low half-maximal inhibitory concentration values for the treatment of other cancers, which are not yet approved for melanoma treatment, were used for in vitro validation using melanoma cell lines

reported that compared with control mice, Slc30a10 knockout mice are much smaller and have significantly higher levels of systemic Mn, and unexpectedly, Mn accumulation caused severe hypothyroidism in these mice 35 , even though the thyroid is not a primary site of Mn accumulation in human patients

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Brussels sprouts also provide smaller amounts of calcium, phosphorus, zinc, and selenium