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The strong decrease of fluorescence is then caused by the immediate formation of roGFP2 WT (S 2 ) which cannot be kinetically separated from the slower glutathionylation of the roGFP2 moiety (Fig

The researchers found that the elevated ROS level triggered by erastin can stimulate Nedd4 expression by inducing Forkhead Box M1 (FOXM1), an essential regulator for oxidative stress and cancer cell survival