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Among the many putative ncRNA-IGF pathways discussed in this review, some are supported by patient survival analyses and tissue investigations

Wiley Interdiscip Rev Syst Biol Med (2020) 12(4):e1483

Additionally, the triglyceride-glucose (TyG) index, a measure of the relationship between fasting plasma TG and glucose levels (259, 260), was independently linked to a higher prevalence of depression among T2DM patients, as reported by Jiaju Ren et al

Future investigations will elucidate the molecular mechanism of glutamine addiction by identifying the death pathways activating during the impairment of glutamine catabolism or when glutamine is limited