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Despite this age-related variability, elevated BHB levels above 1.0 mM were infrequent across the cohort

After further washing with PBS, the DAB chromogenic kit was used for color development

On this basis, the preexisting liver diseases, such as ALD or NAFLD, could worsen liver toxicity from opioid abuse, as well as opioid consume could bring further damage to the aforementioned liver diseases with complex and difficult to fully address mechanisms