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Examples of such medications include the following 154,164 : Gabapentin (Neurontin), an anti-seizure drug Fluoxetine (Prozac), citalopram (Celexa), escitalopram (Lexapro), and paroxetine (Paxil), antidepressants in the selective serotonin reuptake inhibitor (SSRI) class Memantine (Namenda), an N-methyl-D-aspartate (NMDA) receptor antagonist Sodium oxybate (Xyrem), an anti-anxiety and sedative Tramadol (Ultram), an opioid pain reliever and SNRI Although over-the-counter analgesics and anti-inflammatory drugs, such as acetaminophen (Tylenol), ibuprofen (Advil), and naproxen (Aleve), are frequently used, these medications have not demonstrated efficacy for reducing fibromyalgia pain in clinical trials