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doi: 10.1016/j.neuron.2015.03.035, 93 MallachA.ZielonkaM.van LieshoutV.AnY.KhooJ

Metabolic and nonmetabolic functions of PSAT1 coordinate signaling cascades to confer EGFR inhibitor resistance and drive progression in lung adenocarcinoma

Intrahippocampal administration of BmK I elevated c-Fos expression and caused significant morphological changes in the hippocampus, leading to neuronal loss in distinct hippocampal subregions and inducing convulsive behaviors in rats ( 50 (median lethal dose) and therapeutic index) are lacking for most isolated scorpion venom components

Structural analyses reveal tight interactions between L-phosphoserines phosphate group and conserved arginine (Arg42, Arg328) and histidine (His41, His327) residues, suggesting that analogs targeting these residues could yield potent inhibitors (77)