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Disclosure of interest: nothing to disclose Poster Session I - ACUTE ISCHEMIC STROKE MANAGEMENT 01.00 - ACUTE ISCHEMIC STROKE MANAGEMENT - 01.02 - ACUTE MANAGEMENT - Thrombolysis or thrombectomy P130 - ESOC25-1330 THE EFFICACY AND SAFETY OF EARLY BLOOD PRESSURE REDUCTION IN ACUTE STROKE WITH DIFFERENT REAL FUNCTION STATUS: A SYSTEMATIC REVIEW AND META-ANALYSIS Jie Yang 1 , Fengkai Mao 2 1 Department of neurology, Sichuan Provincial People's Hospital, School of Medicine,University of Electronic Science and Technology of China, Chengdu, China, Chengdu, China, 2 The First Affiliated Hospital of Chengdu Medical College, Chengdu, China, Chengdu, China Background and Aims: The management of blood pressure in acute stroke with different renal functional states remains controversial

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those with the best evidence of potential benefit include magnesium, coenzyme Q10 (CoQ10), vitamin D, and melatonin

Data come from animal studies (often using subcutaneous injections) and user reports