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Experimental approaches in this area often include second messenger analysis, such as cyclic AMP quantification, as well as kinase activation profiling and transcriptional response studies

Chemotactic activity of S100A7 (Psoriasin) is mediated by the receptor for advanced glycation end products and potentiates inflammation with highly homologous but functionally distinct S100A15

(B) Oligodendrocyte cell death caused by activated astrocytes and microglia in response to oligodendrocyte damage, which we term toxic innate immunity and (C) oligodendrocyte cell death caused by astrocytes and microglia following a direct effect of cuprizone on these cells, which we term primary immunocytopathy

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