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PMID 15294905

Acknowledgements The authors are grateful for the assistance of staff from the Experimental Animal Center and Analysis & Testing Center of Nanjing Medical University, Anhui Medical University, and Chungbuk National University

Front hormone Res (2014) 43:10724

Within the innate immune response, NLRP3 inflammasomes, innate immune components expressed by macrophages and microglia, mediate caspase-1 activation and promote the secretion of pro-inflammatory cytokines within the CNS, thereby contributing to both systemic and neuroinflammatory responses (36, 37)