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Based on the lovastatin-mediated increase in TG content, the administration of the chemically modified TG-lowering drug fenofibrate, a lipid-regulating fibric acid derivative used for the treatment of patients with hypertriglyceridemia, resulted in a strong synergistic anti-tumor effect, maximizing the killing of MM cells, when combined to lovastatin and PIs [79]

Specifically, during anesthesia, changes in hemodynamics, respiration, and metabolism may have a greater impact on neurodevelopment than the anesthetic drugs themselves (Weiss et al