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HGF/c-Met pathway is one of the most dysregulated pathways in human malignancies, which include, but are not limited to: bladder, breast, cervical, colorectal, endometrial, esophageal, gastric, head and neck, kidney, liver, lung, nasopharyngeal, ovarian, pancreatic, prostate, and thyroid cancers ( Activation of Met in cancer occurs most often through ligand autocrine or paracrine activation

In animal models, faster regeneration of muscle fibers, tendons, and connective tissues has been observed

En investigacin se combinan porque uno favorece la formacin de vasos nuevos y el otro la migracin de clulas al sitio de la lesin