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HanAll's second FcRn inhibitor HL161ANS to be added to the development program of its licensed partner [press release]

Albert DH, Goodwin NC, Davies AM, Rowe J, Feuer G, Boyiadzis M, Dorritie KA, Mancini M, Gandour-Edwards R, Jonas BA, Borthakur G , Aldoss I, Rizzieri DA, Odenike O, Prebet T, Singh S, Popovic R, Shen YU, McDaniel KF, Kati WM, Modi DA, Motwani M, Wolff JE, Frost DJ

Most will not volunteer the information partly because they do not consider it clinically relevant, and partly because they anticipate judgment

Despite the promising preclinical evidence regarding the efficacy of these natural compounds, translating the findings into clinical practice remains limited by several challenges, including issues related to bioavailability, optimal dosing, standardization of extracts, and the need for well-designed clinical trials to validate the efficacy and safety of the therapies in diverse asthma phenotypes