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J Cancer Res Clin Oncol (2018) 144(12):232937

This type of binding is considered base-off/His-on and is important for the catalytic activity of the enzymes

The enzyme system through which they are generated is cytochrome P-450

It is hypothesized that HOXA10 could drive the misplacing of endometrial cells during embryonic life and causing endometriosis, but there is currently no in vivo proof that HOXA10 dysregulation during uterine development may be a possible contributor to the etiology of endometriosis later in life [79, 80]