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Retrieved 17 November 2025

Vigorous agitation degrades peptide integrity, reducing potency before administration

In vivo endothelial cell-specific knockout of MET (through the generation of Tie-Cre Met fl/fl mice) led to normalised vasculature, reduced intra-tumoural hypoxia, slowed glioblastoma growth and importantly, sensitised glioblastoma tumours to temozolomide treatment, prolonging mouse survival [40]