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Subjects were recruited for this study on the basis of a pre-existing knee joint discomfort, no shorter than 3 weeks and not related to injury

Due to the generally higher metabolic activity in cancer cells and the increased levels of ROS associated with cancer progression, they may be more susceptible to ferroptosis ( 6 MM and ferroptosis 6.1 Lipid metabolism pathway 6.1.1 AA pathway Studies have demonstrated significant reductions in key PUFAs, including ferroptosis-inducing AA, within bone marrow aspirates of MM patients ( Intriguingly, MM plasma cells exhibit elevated GPX4 and xCT levels compared to normal counterparts