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Ruzzo, E

We appreciate the recommendation and may take this comment into consideration in future rulemaking

Among the biochemical endophenotypes described in ASD, hyperserotonemia 4,5,6,7,8 is the most replicated 9,10 and is reported in almost half of the patients 4,5,6,7,8

On the other hand, music may indirectly improve the functional state of brain circuits by regulating neurotransmitters, inflammatory factors, and gut microbiota (Merheb et al., 2019)

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