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doi:10.1016/j.ceca.2012.02.008, PMID: 22480931 Jin M, Yaung J, Kannan R, He S, Ryan SJ, Hinton DR (2005) Hepatocyte growth factor protects RPE cells from apoptosis induced by glutathione depletion

Elevated glutathione renders cells more resistant against, e.g., mitochondrial inhibition, oxidative, or proteasomal stress

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Additionally, the study revealed other metabolites with significant changes: taurine and ribonic acid, which were increased in PD patients (fold change 2.8 and 3.2, respectively), suggesting alterations in bile acid metabolism and potential disruptions in the pentose phosphate pathway