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Moreover, co-encapsulation of synbiotics and L-carnitine as a single microcapsule could be considered as a conceivable delivery system to enhance the stability and efficacy of synbiotics as well as to reduce the cost of the final product

Dong et al

Poor dietary habits Inadequate exercise Insomnia and sleep disturbance Thyroid and other hormones including sex hormone deficiency-estrogen and progesterone in women and testosterone and DHEA in men and women Nutrient deficiency (B vitamins, especially B12, magnesium), Mitochondrial dysfunction- poor diet, alcohol excess and unique genetic nutrient requirements Food allergy and gluten intolerance and inflammation Digestive issues- malabsorption, leaky gut and microbiota dysbiosis Infections (Lyme, EBV,CMV) Chronic Fatigue Syndrome Mold and other allergies Heavy metals (lead, mercury, cadmium) and other toxins Major depression and anxiety disorders Inflammation from poor diet, stress, lack exercise Stress and poor adaptation, adrenal fatigue/dysfunction and allostatic load Each of these problems is treatable with the appropriate evaluation and both natural and hormonal therapies

PMID 15591001