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While Methycobal Injection is the standard treatment in Japan, accessing it requires proper medical consultation

In Nrf2-knockdown cells, the inhibitory effects of LicoA on cellular ROS and lipid peroxidase levels were largely abolished (Figures 6AE), and its regulatory effects on transferrin receptor, GPX4, and xCT were nearly eliminated (Figures 6FH)

The obtained results indicate that high seed vigour related to the mode of action of NO and its derivatives is closely linked to the maintenance of higher GSH levels