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doi: 10.1080/00071668.2023.2191308 73 ZhaoYTianXYanYTianSLiuDXuJ

122,123,124 Mammalian CYPs are a family of heme-containing NAD(P)H-dependent monooxygenases that metabolize numerous endogenous metabolites, including fatty acids and steroids, and exogenous substrates, including carcinogens, pesticides and drugs, resulting in continuous production of ROS