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One study showed NR at 300 mg/day increased human blood NAD+ ~50% after 8 weeks, whereas higher doses (1000 mg/day) roughly doubled NAD+ levels

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This IGF-1 independence is the single most important experimental advantage of the AOD 9604 10mg research compound for researchers designing metabolic studies: the absence of IGF-1 elevation means that downstream anabolic, mitogenic, or glucose-modulating confounds associated with full-length hGH are not present in AOD-9604 experimental models