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This mechanism increases IGF-1, supporting muscle regeneration, fat metabolism, and tissue repair

Ubiquitination comprises a multilayered biochemical machinery with E1 activating, E2 conjugating enzymes, E3 ubiquitin ligases, deubiquitinases, and a robust ubiquitin code 30 , as well as an ever-growing molecular repertoire of ubiquitinated molecular species 31

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