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Manufacturing was soon halted in 2002 due to a combination of factors, including an efficacy below 80%, achieved only after multiple doses, limited strain coverage, and no availability for children, a critical population not included in safety and efficacy testing

You can read the full article at Researchers conducted a study to evaluate the effectiveness and safety of tesofensine, a drug that inhibits the reuptake of certain chemicals in the brain (noradrenaline, dopamine, and serotonin), in treating obesity

Any therapeutic use occurs under physician supervision as off-label research application requiring comprehensive informed consent, medical monitoring, and understanding that the peptide is not an approved pharmaceutical agent

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