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Asparagine products ( S )-6-Oxohexahydropyrimidine-4-carboxylic acid 11 : The title compound is observed after 12 h, when exposing asparagine (4.34 mM) to HCHO (10 equiv.)

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However, it remains unclear at this point whether endogenous GSSG molecules drove the learned aversion behavior directly through an interaction with the NMR-1 receptor or indirectly through other neurons via neural circuit networks

thus, the phenotype is manifest fully in males whereas female heterozygotes display varying degrees of G6PD deficiency, due to alternate X-chromosome inactivation 3,4